The synaptic cleft is the region between the axon terminus of the signaling neuron and the receiving region of the next cell. The next cell doesn’t have to be another neuron, but it can be. Following an action potential in the signaling neuron, neurotransmitter molecules are released by that neuron into the synaptic cleft. The neurotransmitter molecules diffuse across the cleft to stimulate receptor proteins on the receiving cell.
(“Nervous system”)
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